Viscosity is an essential handling property for surgeons. To match the needs and preferences of different surgeons, we supply both standard and low viscosity bone cements, offered with and without antibiotics. C-ment® 3 is our low viscosity bone cement, which is initially more liquid, whereas C-ment® 1 is our standard viscosity cement and initially slightly thicker. All cements comply with the International ISO 5833 Standard for PMMA bone cements, which defines the physical, mechanical, packaging, and labelling requirements.
Low hardening temperature
In order to prevent necrosis of surrounding tissue, the International ISO 5833 (2002) Standard places a limit of 90°C on the hardening temperature of bone cements. The peak exothermic temperature of Leader Biomedical’s Genta C-ment® variants is well below this limit.
Antibiotic bone cements
Most frequently used bone cements contain Gentamicin, an antibiotic covering approximately 75% of all bacteria-based pathogens. Adding Gentamicin to bone cements prevents the adherence of bacteria to the cement surface and surrounding tissue, reducing the risk of bacterial growth and infection. Leader Biomedical’s Genta C-ment® 1 and Genta C-ment® 3 include added antibiotics for local antibiosis. To ensure effective antibiosis without compromising the mechanical strength of the product, we limit the amount of antibiotics to 3-4% of the total powder volume. Genta C-ment® offers a high initial release of antibiotics that steadily decreases over time. The burst release initially reduces the risk of resistant bacterial strains while the extended release helps maintain physiologically relevant local concentration of antibiotics needed for sufficient prophylaxis
All products are subject to registration and availability, and may vary by country. Consult your local Leader Biomedical contact or email us at firstname.lastname@example.org